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Citalopram and Escitalopram are noted for their cardiac considerations, particularly at higher doses, which may influence their use in patients with preexisting heart conditions

Dimitris Papamargaritis, an associate professor in diabetes and endocrinology at the University of Leicester, says animal studies suggest that amylin analogs can spare muscle, which is why several companies have decided to look at amylin with a fresh set of eyes

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The study compared the risk of major adverse cardiovascular events (MACE) in people with overweight or obesity and established cardiovascular disease (CVD) but without diabetes, using Wegovy (semaglutide 2.4 mg) versus tirzepatide