Elabescience , 100
Animal studies show IGF-1 LR3 can cause organ growth and changes in insulin and blood sugar levels
However, further studies are needed to evaluate the pro-oxidant roles of p53 , Bax , and Bcl-2 proteins in response to GLP exposure, particularly in herbicide-exposed workers, to better understand the genotoxic mechanisms and their potential association with the increased incidence of cancer in humans
The idea that misfolded -synuclein might travel from gut to brain via the vagus (Braak's hypothesis) has strong experimental support in rodents and mixed evidence in humans
The Real Connection: Hormones, PCOS, and Indirect Effects Now, this is where the conversation gets more interesting and moves beyond a simple 'yes' or 'no.' While spironolactone doesn't directly burn fat, its hormonal effects can play a supportive, albeit indirect, role for some people, particularly those with PCOS