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Clinical trials would need to assess both hemodynamic parameters and clinical outcomes including walking distance, pain scores, and amputation rates to establish therapeutic benefit

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In the 27 European Union countries, a range of sources estimate an incidence of 4.67.4 people per 100,000 of the population, [88] [89] suggesting that approximately 30,00035,000 new patients will be diagnosed with IPF each year

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Some may notice reduced shedding within a few weeks, but visible improvement in thickness and strength may take several months