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Moreover, expression of Ggt1 in mouse tumours did not depend on Gclc expression or the site of tumour growth (Extended Data Fig

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For example, copper nanoparticles CuNP@PST formed from PST001 extracted from the embryo of Tamarindus indica seeds and CuSO 4 5H 2 O, can upregulate the M1 marker iNOS when co-cultured with macrophages in vitro and can stimulate humoral and cellular immunity after administration in vivo , leading to an increase in CD4 + T and CD8 + T cells, enhanced expression of cytokines IL-2, IFN-, IL-4, IL-12, IL-6, Eotaxin, MIP-2, RANTES, TNF-, and thrombopoietin, thereby reducing tumor burden and significantly prolonging the survival of tumor-bearing mice (200)

Third, each LDSF may influence multiple targets within the cardiovascular system and show pleiotropic effects through different molecular mechanisms

Bovine milk is generally considered to be a potentially scalable source of sEVs serving as drug delivery vehicles