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The GLP-1 receptor: a key target in glucose and appetite regulation The glucagon-like peptide-1 receptor (GLP-1R) is a GPCR found primarily in pancreatic -cells, brain, heart, kidney, and the gastrointestinal tract

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GLP-1 agonists facilitate rapid weight loss, averaging 15 to 25% of body weight

(2025) 'Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial' [Accessed 19 Jan