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The etiology of IR in CKD is multifactorial, depending on classical and CKD-peculiar risk factors, such as physical inactivity, inflammation and oxidative stress, adipokine derangements, vitamin D deficiency, metabolic acidosis, anemia and microbial toxins (Spoto et al., 2016)

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By enhancing feelings of fullness and reducing hunger, Semaglutide can significantly aid in weight loss efforts when combined with a healthy diet and regular exercise

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