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Side effects, the boxed warning, and who should steer clear The most common complaints are gastrointestinal: nausea, vomiting, diarrhea, constipation, and abdominal pain

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In the STEP trials (semaglutide) and SURMOUNT trials (tirzepatide) for obesity, participants with baseline binge eating behaviors showed improvements in eating-related measures alongside weight loss, as assessed by questionnaires such as the Control of Eating Questionnaire

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10.1152/jappl.1993.75.6.2419 J Appl Physiol