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It should not be expected to reverse severe osteoarthritis, regrow advanced cartilage loss, correct major joint deformity, heal a complete tendon rupture without appropriate orthopedic management, or replace surgery when surgery is clearly indicated

Indeed, ALT telomeres have a relaxed telomeric chromatin configuration (compared to telomerase positive and normal cells) making them more susceptible to DNA damage and telomere elongation through ALT (Lin et al 2021

As one of the most intriguing compounds in the biohacker toolkit, it has gained widespread interest in the research community for its potential role in supporting tissue regeneration , angiogenesis , and cellular protection across multiple systems