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7.5 Saponins: guardians of mitochondrial integrity and lipid peroxidation Saponins protect against ALD by inhibiting CYP2E1 to reduce ROS generation during ethanol metabolism, while PPAR- activation promotes fatty acid -oxidation and HDL synthesis (Yang et al., 2021a

It's recommended to avoid or limit alcohol intake while using this medicine

Nevertheless, there is also major side effect of this treatment such as gaining weight [52]

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