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As with any medication, adjusting to GLP-1 therapy can come with some side effects, particularly digestive issues like nausea, diarrhea, and constipation

PMID: 28851949

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Who should avoid semaglutide Semaglutide should not be used by people with: Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Personal or family history of medullary thyroid carcinoma (MTC) Serious allergic reactions to semaglutide Be extra careful if you have pancreatic or kidney problems, diabetic retinopathy, or are pregnant or breastfeeding

Stopping copper peptide use allows gradual return toward baseline as the collagen-building stimulation ceases