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Inclusion criteria required participants to be over age 18, read and speak English, have a Hoehn & Yahr score between 2 and 3 (bilateral disease, not severely disabled), and have three or more of the required positive criteria for the diagnosis of definite PD from Step 3 of the UK Brain Bank Diagnostic Criteria for PD

Some individuals may also experience changes in blood sugar levels

PT-141 is also notable as the only one of the three FDA-approved for women sold as Vyleesi for hypoactive sexual desire disorder in premenopausal women

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Abrupt cessation may lead to weight regain (70%-80% of lost weight within one year), rebound hunger, and metabolic changes