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Here, we found infusions of GIP(3-30)NH 2 to cause higher plasma glucose levels, indicating a glucose-lowering effect of endogenous GIP

If confirmed in Phase III, elecoglipron could offer an additional oral GLP1 option for patients and clinicians seeking alternatives to injectable regimens. Beyond efficacy trials, AstraZenecas Appendix highlights an extensive supporting programme for elecoglipron, including Phase I studies in healthy volunteers, renal and hepatic impairment, bioavailability, and key drugdrug interaction assessments

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