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This is a critical distinction when designing an experiment

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Whether this tradeoff makes sense depends on individual priorities, including needle aversion, convenience requirements, and budget considerations

Theres Contrave, a prescription weight-loss pill which is made of the same stuff as the antidepressant Wellbutrin

John Eng ran a chemical screen through the venom of a Sonoran Desert lizard, found a molecule he described precisely but couldnt explain, and his careful final sentence predicting the mammalian analog pointed at a hormone whose therapeutic consequences we are still mapping thirty years on