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Initial studies reported a crucial role of RIPK1 for hematopoiesis in general and for erythropoiesis in particular, since its deficiency is associated with anemia [152]

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Ehrlich C, Iker E, Herbst KL, Kahn LA, Sears DD, Kenyon M

The conspicuous blood cortisol awakening response is the net daily increase in blood cortisol within 1 hour of awakening (282)

In addition, androgens promote lipolysis and glucose uptake by upregulating the expression of key enzymes and proteins involved in glucose and lipid metabolism, such as ATGL and GLUT4, to alleviate glycolipotoxicity, thus eventually achieving a protective effect on the structural integrity and function of the electron transfer chain ( Figure 2 )