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This development led to a surge of interest, research, and funding for drugs that could treat these metabolic diseases through different biological pathways

The HGH alternatives guide compares peptide-based approaches against direct GH replacement

Mithal explains

Additional supplementation may also be indicated with a low-meat nutrition (vegetarian, vegan)

To those who are still bleating that we should keep trying diet and exercise before resorting to use of anti obesity medications or that we can maintain long term weight loss effected by use of medication by ceasing medication and relying on diet and exercise alone- please look up all the research which shows that lifestyle intervention alone can only effect 5-7% weight loss and this weight will also be regained in the next year or two