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Patients using oral contraceptives should be aware that tirzepatide may reduce the effectiveness of these medications, particularly during initiation and dose escalation

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Untreated, it usually leads to premature CAD (in women before 60 years of age, and in men before 55 years) which means an up to 10-fold increase in the risk of CAD [275]

Without exercise, especially strength training, you may lose muscle along with fat