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Biomarker and Genetic Context: Why Responses Vary So Widely Individual differences in glutathione metabolism, melanin synthesis genes, and antioxidant capacity significantly influence how any person responds to glutathione supplementation

One review found that B6 may be especially helpful for premenopausal women with depression, and the authors recommended further research into B6 as a therapy for hormone-related depression in women

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Results: Short-term (12-week) use for kickstarting weight loss

Possible complications heart failure severe neurological deficits gastric cancer type 1 diabetes rheumatoid arthritis myasthenia gravis (a chronic condition causing muscle weakness) Hashimotos disease (an autoimmune condition affecting the thyroid) A pregnant or nursing person with a B12 deficiency When a person receives treatment for a B12 deficiency, they generally recover well and cease to have symptoms, although they may need to continue to use B12 nutritional supplements