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In vitro and in vivo models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expressions of GCLC, GCLM and SLC7A11 were down-regulated, thereby disrupting the metabolism of glutathione

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If you are healthy, your body makes what it needsprovided you feed it protein and get adequate sleep

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The mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving cerebral blood flow, and modulation of dopamine and serotonin systems