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They dont have TPE

CrossRef Metabolic, hormonal characteristics and genetic variants of TCF7L2 associated with development of gestational diabetes mellitus in Mexican women Ruth ReyesLpez, Elva PrezLuque, Juan Manuel Malacara Diabetes/Metabolism Research and Reviews.2014

This combination is more effective at lowering blood pressure than either medication alone, so it can be useful for patients with moderate to severe hypertension

This may reflect differences in the prescription of glucose-lowering medication in a specialist versus non-specialist setting, with only 34.2% of participants in PIONEER REAL Netherlands treated by diabetes specialists

The investigators conducted emulation target trials, a statistical approach that mimics a randomized clinical trial