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Molecules 26(4):1054 Mohan GK, Pallavi E, Kumar R, Ramesh M, Venkatesh S (2007) Hepatoprotective activity of Ficus carica Linn leaf extract against carbon tetrachloride-induced hepatotoxicity in rats

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This dual inhibition disrupts NF-B signaling and stabilizes pro-apoptotic factors like p53, creating a feed-forward loop of oxidative stress and proteotoxic crisis [121, 122]