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And IL-22 has a dual role in UC, which can not only play a protective role by promoting the recovery of the intestinal barrier, but also may exacerbate the inflammatory response by upregulating neutrophil-active chemokines such as Cxcl1

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Conversely, adventitial pericytes (APC) counteract calcification by triggering an anti-calcific effect through the upregulation of microRNA-132-3p (68)