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Age-dependent upregulation of p53 and cytochrome c release and susceptibility to apoptosis in skeletal muscle fiber of aged rats: role of carnitine and lipoic acid
Autophagy 7 , 211 (2011)
Studies have found that DES IGF-1 binds IGF-1R with 210 times higher affinity than the native sequence in direct binding assays (Carlsson-Skwirut et al., 1989)
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[1] Often there is sudden onset of pain and walking is difficult
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