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Mechanistically, Clostridium probiotics may modulate ADs via multiple therapeutic mechanisms, including regulating gut microbiota composition, replenishing beneficial metabolites to restore intestinal barrier integrity, correcting dysregulated immune cell differentiation and homeostasis, and balancing pro- and anti-inflammatory cytokine levels

Three DNMTs include 2 de novo methyltransferases, Dnmt3a and Dnmt3b [44], and 1 classical maintenance methyltransferase, Dnmt1 [45]

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Erratum in eClinicalMedicine 2024, 78, 102958