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Testing for vitamin B12 or folate deficiency is not routinely included in blood work ordered at an annual physical exam

The use of blood concentrations of vitamins and their respective functional indicators to define folate and vitamin B 12 status

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Notably, this chain-breaking activity is amplified by synergistic interactions with ascorbic acid, which regenerates -TOH from its oxidized tocopheryl radical, enhancing redox cycling efficacy [116]