Researchers found consistent reductions in binge-eating-related symptoms across 25 clinical trials, suggesting GLP-1 medicines could one day complement psychological treatment
However, it doesnt actually start the carthe gas, battery, alternator, belts, radiator, and computers all work together to start the car once the key is in the ignition and turned
Kapralov AA, Yang Q, Dar HH, Tyurina YY, Anthonymuthu TS, Kim R, et al
PT-141: The Arousal Circuit PT-141 bypasses hormones entirely: PT-141 binds MC4R (melanocortin-4 receptor) in the hypothalamus and limbic system Activates sexual arousal pathways particularly in the medial preoptic area and paraventricular nucleus Downstream signals travel via spinal cord pathways to produce physiological arousal (erection in males, genital arousal in females) No hormonal changes LH, FSH, testosterone, and estrogen are unaffected PT-141 works like a "desire switch" it directly activates the neural circuit for sexual arousal without touching the reproductive hormone axis
And although it was coined nearly 20 years ago, it's still relevant, perhaps even more so, in the era of GLP-1s: Eat food
