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Geer, R

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Constipation can often improve with: adequate fluid intake gradually increasing fibre intake daily movement regular meals foods with a natural laxative effect, such as prunes, figs, apricots and pears If symptoms are significant or long lasting, discuss this with your healthcare team, as individual advice or medical treatment may be needed

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Berberine treatment also decreases the excretion of urinary microalbumin (Qin et al., 2020)

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The above results would collectively suggest that BoCA, in part, leads to gut microbiome reorganization, which increased gut-host production of PAGln

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