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JHR symptoms include fever, chills, nausea and vomiting, headache, tachycardia (fast heartbeat), hypotension, and hyperventilation 1

Yes, it's something additional to do, but highly necessary in a global, fragmented supply chain with what I would consider minimal barriers to entry for health-implicating products

Neurogenic inflammation in acute migraine attacks is characterized by a TVS activation-induced release of neuropeptides, such as CGRP and substance P, from trigeminal nerve fibers at the dura, which causes increased vascular permeability, plasma protein extravasation, leukocyte infiltration, vasodilation, mast cell degranulation, activation of meningeal nociceptors, and the subsequent release of inflammatory mediators (5)

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Wade MR, Degroot A, Nomikos GG