tirzepatide cvot results SURPASS-CVOT Published: Large Trial Confirms CVD Efficacy of Diabetes Dialogue: Tirzepatide and SURPASS-CVOT

Whilst it is widely assumed that endogenous peripheral GLP-1 interacts with the central GLP-1 system (via vagal and/or endocrine activation of PPG NTS neurons) to control eating under physiological conditions, this link remains subject to debate and has not been demonstrated empirically 4,1315

Many thanks to my co-authors for the great collaboration, and to the editors and reviewers for their valuable feedback

What Its Studied For FDA-approved tirzepatide has been studied in the SURMOUNT (weight management) and SURPASS (type 2 diabetes) trial programs and carries formal labeling for those uses

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