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On the other hand a GLP1-ANP axis has been only demonstrated in hypertensive mice, in which GLP-1R activation in the atria leads to ANP secretion and stimulation of natriuresis and vasodilation in the consequence

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231 , 232 Most authorities wait at least several months before initiating therapy so that the adverse effects of the antiretroviral therapy are not confused with those caused by peginterferon or ribavirin