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Metformin for diabetes and proton pump inhibitors for acid reflux can both interfere with B12 absorption over time
Frequently Asked Questions
5-Amino-1MQ was developed as a pharmacological tool to inhibit NNMT activity, and preclinical studies have demonstrated that oral administration of 5-Amino-1MQ to obese rodents produces dose-dependent reductions in body weight and fat mass, improvements in glucose metabolism and insulin sensitivity, and increases in energy expenditure - remarkably, these effects occur without changes in food intake, indicating that 5-Amino-1MQ works through metabolic enhancement and increased caloric burn rather than appetite suppression
It is particularly useful in cases where oral supplements are insufficient or rapid delivery of B12 is required
I discuss this in my video The Best Type of Vitamin B12: Cyanocobalamin or Methylcobalamin
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