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From a neuroscience perspective, less adiposity means less peripheral inflammation, less mechanical joint stress, less nociceptor drive, and potentially less central sensitization

The idea is that a single treatment delivered directly to the insulin-producing cells in the pancreas would never need to be repeated

Retatrutide weight loss from Phase 2 and TRIUMPH-4 Retatrutide entered the clinical picture with a Phase 2 trial published in the New England Journal of Medicine

The primary means by which retatrutide aids weight management is through its impact on appetite-regulating hormones and metabolic handling of food

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