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Oxyntomodulin has already shown to reduce food intake and bodyweight in rodents and humans (75, 76)

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In brief, serial dilutions of G49 and Fc-GLP1 in assay buffer (as above) were added in duplicate to CHO cells recombinantly expressing human GLP-1R and incubated for 30 min at RT before detection with the cAMP dynamic 2 HTRF assay

The Strategic Funding Increase program was designed specifically to bridge this gap, combining government SBIR funding with private matching capital to give high-potential companies the runway to reach procurement-ready status