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[7] PharmaCotherapia d.o.o., Phase I, Pilot Study in Healthy Volunteers, to Assess the Safety and Pharmacokinetics of PCO-02, Which Active Ingredient is BPC-157, a Penta-deca-peptide From Gastric Source., clinicaltrials.gov, Clinical trial registration NCT02637284, Dec

A 1997 study in Journal of Physiology (Paris) reported effects of the pentadecapeptide in non-steroidal anti-inflammatory-agent gastrointestinal-lesion and adjuvant-arthritis models in rats, an early signal that the group intended to characterize the compound well beyond the gastrointestinal tract [3]

Overdosing increases side effects and potentially creates safety concerns

Bis-allylic carbon atoms are carbon atoms in a carbon chain that are single-bonded on both sides to carbon atoms that are double-bonded to their other neighbor

These values for GSSG are somewhat higher, but within the range previously reported, 77 38 M [20]