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These compounds are classified on the basis of their characteristic skeletons and mainly include saponins, alkaloids, phenols, and flavonoids

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"Most of these changes are caused by the weight loss itself, along with secondary effects such as metabolic and nutritional changes that can occur with rapid weight loss," Son says

After OGD treatment, the number of Ki-67-positive endothelial cells significantly decreased, while the intracellular expression levels of senescence markers P21, P53, and the DNA damage indicator -H2AX were markedly elevated (Figure 3B)

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