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For example, a recent meta-analysis of 11 large outcomes trials found that, in those aged 65 years or older, the cardiovascular and/or kidney outcomes benefits of GLP-1 RA or SGLT2i therapy were consistent with the effects seen in the overall trial population [266]

Now production cannot keep up with demand for this instant blockbuster peptide drug, also marketed for weightloss as Wegovy, and the similar GLP-1 drug developed by Lilly, tirzepatide (Zepbound or Mounjaro)

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After 68 weeks, participants receiving a 2.4 mg weekly semaglutide dose experienced a 49% reduction in C-reactive protein (CRP), while those on a 1 mg weekly dose saw a 42% reduction compared to placebo

Exendin-4 inhibits growth and augments apoptosis of ovarian cancer cells