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When your brain has enough glutathione , you can potentially avoid anxiety, depression , and more serious neurodegenerative diseases such as Alzheimers, Huntingtons, and Parkinsons disease.[xvi] How things go bad if you are glutathion deficient Glutathione exists in cells in 2 states: reduced Glutathione (GSH) and o x idized Glutathione disulfide (GSSG)