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A: Main disadvantages include: high cost for long-term use, results arent permanent (maintenance required), potential for uneven whitening without sun protection, rare side effects (nausea, headache), and dependency on clinic visits

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Table 2 Comparison of Hemi-MASI SCORE and its reduction % between both sides of the face in two groups By grading and comparing reduction percentages of Hemi-MASI score

Some prefer injecting near the injury site for localized effects, while others use subcutaneous abdominal injections for systemic distribution

First month follow-up: Most clinics check in at 2-4 weeks to assess tolerance, effectiveness, and side effects