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Due to incomplete mechanistic understanding, no effective therapies to reduce levels of indoxyl sulfate are available

Table 3-2 summarizes those biomarkers of greatest interest in the scientific community (Svetlov et al., 2009): S-100B, neuron-specific enolase, glial fibrillary acidic protein, and myelin basic protein

GLP-1 also has protective effects on the heart and brain, reduces inflammation and cell death, and plays a role in learning, memory, and behavior related to rewards and taste

Start replacing electrolytes at the first sign of loose stools

The illness can cause persistent cognitive impairment and "brain fog", suggesting chronic brain involvement