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The randomized and placebo-controlled design of all included trials and the double-blind design of most of them can also be other strengths and due to the RCT nature of the studies, the drugs used by the patients (especially in diabetic patients), the diet and the level of physical activity of the participants were controlled and in fact their effects were considered and it can be said that the pure effects of L-carnitine was evaluated
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doi: 10.3389/fpsyt.2018.00589 Received 19 May 2018 Accepted 25 October 2018 Published 16 November 2018 Volume 9 - 2018 Edited by Margit Burmeister, University of Michigan, United States Reviewed by Mikhail Pletnikov, Johns Hopkins University, United States
