Exp Parasitol (2010) 126(4):45661
The smaller airways lead down into the alveoli where gas exchange occurs and where surfactants are increasingly required to prevent airway collapse during exhalation (Possmay et al., 2001)
Familial risk was generally higher within generations (sibling-sibling) than between generations (parent-child), and familial risk increased as the number of affected first-degree relatives increased [16, 17]
Pappolla MA, Matsubara E, Vidal R, Pacheco-Quinto J, Poeggeler B, Zagorski M, et al
However, patients with low BSA psoriasis and burdensome symptoms who are candidates for biologic therapy (according to the clinicians judgement) may not meet a payers criteria for eligibility to receive advanced psoriasis treatment options [4, 9, 23, 28] Current International Psoriasis Council (IPC), American Academy of Dermatology, and National Psoriasis Foundation treatment guidelines recommend that indicators of psoriasis disease burden beyond BSA, including involvement of high-impact sites and failure of topical therapies, be considered when determining whether patients are eligible for systemic treatment [3, 4]
