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A 2017 meta-analysis of data from 15 trials, including more than 71,000 participants at risk of or with existing CVD, showed that B-vitamin supplementation had no significant effect on risk of myocardial infarction (heart attack) or all-cause mortality but reduced risk of stroke by 10% (RR, 0.90

The 1998 RDAs for vitamin B6 for adults, in milligrams, are 1.3 mg for men and women ages 9-50 and 1.7 mg and 1.5 mg for men and women over the age of 51, respectively