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191 , 192 Inadequate or poor sleep may compromise the brain's ability to remove betaamyloid and other toxins, enabling levels of toxins to remain elevated

Endotoxins can also cause oxidative stress, increasing the demand for glutathione to neutralize free radicals produced

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By delivering intact glutathione directly into the mast cells via liposomal membrane fusion, the supplement helps to quench the oxidative "danger signals" that provoke degranulation

The redox cycling enzymes thioredoxin, thioredoxin reductase, sulfiredoxin, peroxiredoxin, GSH peroxidase, superoxide dismutase 1, and catalase, and several GSH S-transferases, which are the enzymes mediating the elimination of ROS, are all Nrf2 targets (242)