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They're typically marketed as a stack the claim being that they work on complementary pathways and produce a bigger pulse of GH together than either does alone

However, in most cases, the effects typically diminish within a few days

The STEP program (Semaglutide Treatment Effect in People with obesity) followed participants for up to 68 weeks, with those staying on medication maintaining 80% of their weight loss, while those who stopped regained nearly two-thirds of the weight within one year

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This is helpful for type 2 diabetes patients who have trouble with post-meal spikes