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This so-called ETosis is often associated with cell death of the producing MC, and the type of stimulus potentially determines the ratio of surviving vs

Pickart and colleagues (Nature, 1980, PMID 7453802) reported facilitated copper uptake into cultured cells, and Simon and colleagues (Life Sci, 2000, PMID 11045606) reported upregulated MMP-2 alongside its tissue inhibitors in fibroblast culture

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Instead, it is a synthetic small molecule and has no amino-acid sequence

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