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Gastrointestinal effects: the main titration bottleneck Nausea, diarrhea, constipation, and vomiting run around 40 to 44% overall, dose-dependent in how many people report them but mild-dominant in severity: severe events stay at or below about 1.7% in any category even at the top dose. In the obesity program the by-dose rates run nausea 25/29/28%, diarrhea 19/21/23%, and vomiting 8/11/13% at 5/10/15 mg. They concentrate during escalation and ease with time on a held dose

Many patients hit a comfortable rhythm of 2 small meals plus a protein-rich snack daily

Our body and state of health are all so different, I dont think there is really any way to know beforehand how you will feel from trying this out

Some travelers do both destinations in a single trip

2002 Nov-Dec;21(6):216-8