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The lower rate of treatment discontinuation in the trials may potentially be explained by patient monitoring and encouragement to adhere to the protocol, and/or selective inclusion of patients who are more likely to adhere to treatment

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doi: 10.1007/s12011-019-01887-0

This variant of GHS-R has been shown to transduce the GH-releasing effect of synthetic growth hormone secretagogues (GHSs) as well as ghrelin and also plays a role in neuroendocrine and appetite-stimulating activities centrally

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