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In dextran sulphate sodium (DSS)-induced colitis mice, the most commonly used preclinical IBD model, injected MOTS-c significantly reduced colon shortening and histological damage, lowered pro-inflammatory cytokines and plasma myeloperoxidase, and curbed macrophage and neutrophil activity

Vitamins and minerals functioning as antioxidants with supplementation considerations

Acute administration of a Y1-R agonist may also reduce the rate of insulin secretion by pancreatic -cells (Guida, Stephen et al

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For kinetic experiments with fecal communities, fecal slurries prepared as described above were used instead of starter cultures