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Even when fat loss is progressing, some people begin to notice subtle physical changes like fatigue, slower recovery, reduced endurance, or feeling weaker during workouts

Four patients, retrospectively reviewed, with no control group, is a signal and nothing more

A Dionex UltiMate 3000 506 LC System (Thermo Scientific) and a Q Exactive Orbitrap mass spectrometer (Thermo Scientific) operated in negative mode was used for targeted measurement

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