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The goal is almost always to leverage the specific function of the MC1R without activating other systems
Cureus, [online] 17(1).
10.1126/science.aan4665 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.Herrmann A, Wllner V, Moos S, Graf J, Chen J, Kieseier B, et al
"Placebo-controlled" means the control group receives an identical-looking but inactive product, so any improvement in the treatment group can be attributed to the active ingredients rather than the act of applying something
The FDA has stated explicitly that these salt forms are "different active ingredients" and that the agency "is not aware of any lawful basis for their use in compounding." The practical concern is that salt forms may have different chemical and pharmacological properties
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