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& Wolf, C

doi: 10.1016/0168-3659(90)90015-L

Among people who started the trial with arthritis in their knees, reported pain declined by about 70%

Who May Need Extra Caution Extra caution may be needed for patients who are pregnant or trying to become pregnant, have active cancer or a cancer history requiring specialist input, have autoimmune disease, have clotting concerns, use immune-modifying medication, have uncontrolled diabetes, have significant kidney or liver disease, or are scheduled for surgery